Abstract
We report a case of rash probably induced by ciprofloxacin and/or salazopyrin administration in a patient with infectious mononucleosis. A 22 year woman developed a maculopapular and petechial eruption in the 3-rd day of ciprofloxacin (given for a genital tract infection) and the 32-nd day of salazopyrin (for a spondylodiscitis). Subsequently she developed a severe hepatitis, shock, and very severe leucocytosis (88 000/mmc) that occasioned haematological investigations for a lymphoproliferative syndrome.
MeSH terms
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Adult
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Anti-Infective Agents / administration & dosage
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Anti-Infective Agents / adverse effects*
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Antirheumatic Agents / administration & dosage
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Antirheumatic Agents / adverse effects*
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Chemical and Drug Induced Liver Injury / etiology
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Ciprofloxacin / administration & dosage
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Ciprofloxacin / adverse effects*
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Diagnosis, Differential
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Discitis / drug therapy
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Drug Eruptions / diagnosis
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Drug Eruptions / etiology
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Drug Therapy, Combination
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Female
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Genital Diseases, Female / drug therapy
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Humans
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Infectious Mononucleosis / complications*
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Infectious Mononucleosis / diagnosis*
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Pruritus / chemically induced
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Severity of Illness Index
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Shock / chemically induced
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Sulfasalazine / administration & dosage
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Sulfasalazine / adverse effects*
Substances
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Anti-Infective Agents
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Antirheumatic Agents
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Sulfasalazine
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Ciprofloxacin