Methotrexate has no antifibrotic effect in bleomycin-induced experimental scleroderma

J Rheumatol. 2010 Mar;37(3):678-9. doi: 10.3899/jrheum.090961.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antirheumatic Agents / administration & dosage
  • Antirheumatic Agents / therapeutic use*
  • Bleomycin / adverse effects*
  • Disease Models, Animal
  • Fibrosis
  • Injections, Intraperitoneal
  • Methotrexate / administration & dosage
  • Methotrexate / therapeutic use*
  • Mice
  • Mice, Inbred BALB C
  • Scleroderma, Systemic / chemically induced*
  • Scleroderma, Systemic / drug therapy*
  • Scleroderma, Systemic / pathology
  • Skin / pathology
  • Treatment Outcome

Substances

  • Antirheumatic Agents
  • Bleomycin
  • Methotrexate