A single-step synthesis of enynes: Pd-catalyzed arylalkynylation of aryl iodides, internal alkynes, and alkynylsilanes

Norio Sakai; Ryosuke Komatsu; Naoki Uchida; Reiko Ikeda; Takeo Konakahara

doi:10.1021/ol100180j

A single-step synthesis of enynes: Pd-catalyzed arylalkynylation of aryl iodides, internal alkynes, and alkynylsilanes

Org Lett. 2010 Mar 19;12(6):1300-3. doi: 10.1021/ol100180j.

Authors

Norio Sakai¹, Ryosuke Komatsu, Naoki Uchida, Reiko Ikeda, Takeo Konakahara

Affiliation

¹ Department of Pure and Applied Chemistry, Faculty of Science and Technology, Tokyo University of Science (RIKADAI), Noda, Chiba 278-8510, Japan. sakachem@rs.noda.tus.ac.jp

PMID: 20184344
DOI: 10.1021/ol100180j

Abstract

An unprecedented single-step synthesis of enyne derivatives through Pd-catalyzed arylalkynylation of aryl iodides, internal alkynes, and alkynylsilanes is described.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkynes / chemical synthesis*
Alkynes / chemistry*
Catalysis
Hydrocarbons, Iodinated / chemistry*
Molecular Structure
Palladium / chemistry*
Silanes / chemistry*
Stereoisomerism

Substances

Alkynes
Hydrocarbons, Iodinated
Silanes
Palladium