Two new sesquiterpene glucosides from the leaves of Nicotiana tabacum

Xin Feng; Jun-Song Wang; Jun Luo; Ling-Yi Kong

doi:10.1080/10286020903002121

Two new sesquiterpene glucosides from the leaves of Nicotiana tabacum

J Asian Nat Prod Res. 2009 Jul;11(7):675-80. doi: 10.1080/10286020903002121.

Authors

Xin Feng¹, Jun-Song Wang, Jun Luo, Ling-Yi Kong

Affiliation

¹ Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.

PMID: 20183306
DOI: 10.1080/10286020903002121

Abstract

Two new sesquiterpene glycosides, 11R,12-dihydroxy-6(7)-spirovetiven-8-one-9-O-beta-D-glucopyranoside (1) and rishitin M1-13-O-beta-D-glucopyranoside (2), have been isolated from the leaves of Nicotiana tabacum. Their structures were established by spectroscopic methods including (1)H, (13)C, and 2D NMR. The absolute configuration of the side chain in compound 1 was determined as R by NOESY and NOE difference spectra.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Drugs, Chinese Herbal / chemistry
Drugs, Chinese Herbal / isolation & purification*
Glucosides / chemistry
Glucosides / isolation & purification*
Molecular Structure
Nicotiana / chemistry*
Nuclear Magnetic Resonance, Biomolecular
Plant Leaves / chemistry
Sesquiterpenes / chemistry
Sesquiterpenes / isolation & purification*
Stereoisomerism

Substances

11R,12-dihydroxy-6(7)-spirovetiven-8-one-9-O-beta-D-glucopyranoside
Drugs, Chinese Herbal
Glucosides
Sesquiterpenes
rishitin M1-13-O-beta-D-glucopyranoside