Trigeminal herpes zoster and Ramsay Hunt syndrome with a lesion in the spinal trigeminal nucleus and tract

J Neurol. 2010 Jun;257(6):1045-6. doi: 10.1007/s00415-010-5487-6. Epub 2010 Feb 13.

Abstract

We report the case of a 77-year-old immuno-competent man who developed herpes zoster in the maxillary and mandibular branches of the trigeminal nerve. Within 3 weeks, he developed ipsilateral peripheral facial palsy, hearing loss, vesicles over the external auditory canal, and pain in the face and ear. A T(2)-weighted MRI of the brain revealed a hyper-intense lesion at the right medulla corresponding to the spinal trigeminal nucleus and tract. Gadolinium enhancement was seen over the right facial nerve. These lesions suggest a possibility of transaxonal spread of the varicella zoster virus between the trigeminal nerve, the facial nerve, and the spinal trigeminal nucleus and tract.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Brain / pathology
  • Facial Nerve / pathology
  • Herpes Zoster / complications
  • Herpes Zoster / pathology*
  • Herpes Zoster Oticus / complications
  • Herpes Zoster Oticus / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neural Pathways / pathology
  • Trigeminal Nerve Diseases / complications
  • Trigeminal Nerve Diseases / pathology*
  • Trigeminal Nucleus, Spinal / pathology*