Cellulase hyperproducing mutants derived from the fungus Trichoderma reesei QM9414 produced large amounts of cellulase at the enzymatic and transcriptional levels

Biosci Biotechnol Biochem. 2010;74(2):419-22. doi: 10.1271/bbb.90655. Epub 2010 Feb 7.

Abstract

Cellulase hyperproducing mutants derived from the fungus Trichoderma reesei QM9414 were analyzed. They exhibited higher filter-paper degrading activity and a lower growth rate than the wild-type QM9414 strain. Transcription of the cellobiohydrolase I and endoglucanase I genes in the mutants was also greater than that of QM9414, suggesting that cellulase hyperproduction by these mutants was regulated at the transcriptional level.

MeSH terms

  • Cellulase / biosynthesis*
  • Cellulase / genetics*
  • Mutation*
  • Transcription, Genetic*
  • Trichoderma / enzymology*
  • Trichoderma / genetics
  • Trichoderma / metabolism

Substances

  • Cellulase