Immunology: TL1A in the inflammatory network in autoimmune diseases

Jagadeesh Bayry

doi:10.1038/nrrheum.2009.263

Immunology: TL1A in the inflammatory network in autoimmune diseases

Nat Rev Rheumatol. 2010 Feb;6(2):67-8. doi: 10.1038/nrrheum.2009.263.

Author

Jagadeesh Bayry¹

Affiliation

¹ INSERM Unité 872, Equipe 16, Centre de Recherche des Cordeliers, 15 rue de l'Ecole de Médicine, Paris, France. jagadeesh.bayry@crc.jussieu.fr

PMID: 20125169
DOI: 10.1038/nrrheum.2009.263

Abstract

Several lines of evidence both from experimental models and from clinical studies reveal that TNF-like ligand 1A (TL1A) and its interaction with death receptor 3 (DR3) is critically involved in the pathogenesis of rheumatoid arthritis and other autoimmune diseases.

Publication types

News
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Arthritis, Rheumatoid / etiology
Arthritis, Rheumatoid / metabolism*
Humans
Receptors, Tumor Necrosis Factor, Member 25 / metabolism*
Tumor Necrosis Factor Ligand Superfamily Member 15 / metabolism*

Substances

Receptors, Tumor Necrosis Factor, Member 25
Tumor Necrosis Factor Ligand Superfamily Member 15