CuCl/CCl(4)-promoted convenient synthesis of sulfonyl amidines from tertiary amines and sulfonyl azides

Xiaoliang Xu; Zhichuang Ge; Dongping Cheng; Lei Ma; Chunshan Lu; Qunfeng Zhang; Nan Yao; Xiaonian Li

doi:10.1021/ol1000236

CuCl/CCl(4)-promoted convenient synthesis of sulfonyl amidines from tertiary amines and sulfonyl azides

Org Lett. 2010 Mar 5;12(5):897-9. doi: 10.1021/ol1000236.

Authors

Xiaoliang Xu¹, Zhichuang Ge, Dongping Cheng, Lei Ma, Chunshan Lu, Qunfeng Zhang, Nan Yao, Xiaonian Li

Affiliation

¹ Institute of Industrial Catalysis, College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, People's Republic of China.

PMID: 20121255
DOI: 10.1021/ol1000236

Abstract

Promoted by CuCl/CCl(4), a variety of sulfonyl azides and tertiary amines were successfully coupled to give sulfonyl amidine derivatives in good to excellent yields. A possible mechanism for this reaction is discussed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amidines / chemical synthesis*
Amidines / chemistry*
Amines / chemistry*
Azides / chemistry*
Carbon Tetrachloride / chemistry*
Catalysis
Copper / chemistry*

Substances

Amidines
Amines
Azides
Copper
cuprous chloride
Carbon Tetrachloride