Classification of osseointegrated implant surfaces: materials, chemistry and topography

Trends Biotechnol. 2010 Apr;28(4):198-206. doi: 10.1016/j.tibtech.2009.12.003. Epub 2010 Jan 29.

Abstract

Since the founding of the osseointegration concept, the characteristics of the interface between bone and implant, and possible ways to improve it, have been of particular interest in dental and orthopaedic implant research. Making use of standardized tools of analysis and terminology, we present here a standardized characterization code for osseointegrated implant surfaces. This code describes the chemical composition of the surface, that is, the core material, such as titanium, and its chemical or biochemical modification through impregnation or coating. This code also defines the physical surface features, at the micro- and nanoscale, such as microroughness, microporosity, nanoroughness, nanotubes, nanoparticles, nanopatterning and fractal architecture. This standardized classification system will allow to clarify unambiguously the identity of any given osseointegrated surface and help to identify the biological outcomes of each surface characteristic.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bone Substitutes / chemistry*
  • Bone Substitutes / classification*
  • Bone Substitutes / standards
  • Coated Materials, Biocompatible / chemistry*
  • Coated Materials, Biocompatible / classification*
  • Coated Materials, Biocompatible / standards
  • Humans
  • Prostheses and Implants / classification*
  • Prostheses and Implants / standards

Substances

  • Bone Substitutes
  • Coated Materials, Biocompatible