PKS and NRPS release mechanisms

Nat Prod Rep. 2010 Feb;27(2):255-78. doi: 10.1039/b912037h. Epub 2009 Dec 4.

Abstract

This review covers the recent literature on the release mechanisms for polyketides and nonribosomal peptides produced by microorganisms. The emphasis is on the novel enzymology and mechanistic insights revealed by the biosynthetic studies of new natural products.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Biological Products*
  • Macrolides / metabolism*
  • Molecular Structure
  • Peptide Biosynthesis, Nucleic Acid-Independent*

Substances

  • Biological Products
  • Macrolides