[Study on epidemiological effect of the freeze-dried attenuated live varicella vaccine]

Zhongguo Yi Miao He Mian Yi. 2009 Jun;15(3):193-5.
[Article in Chinese]

Abstract

Objective: To evaluate the safety and epidemiological effect of the Freeze-dried Live attenuated varicella vaccine.

Methods: A random, double-blind control clinical trial was adopted.

Results: In the observation period, the incidence of varicella was 0.8 per thousand in the experimental group and 8.7 per thousand in control group. There was a significant difference (B.P=0.000017). Vaccine effectiveness (VE(%)) was 90.8%, the lower limit of 95%CI was 88.7%.

Conclusion: The varicella vaccine produced by Changchun keygen biological products co., Ltd. was safe and effective.

Publication types

  • English Abstract
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chickenpox / epidemiology*
  • Chickenpox / immunology
  • Chickenpox / prevention & control*
  • Chickenpox Vaccine / administration & dosage*
  • Chickenpox Vaccine / immunology
  • Child
  • Child, Preschool
  • China / epidemiology
  • Drug Evaluation, Preclinical
  • Female
  • Freeze Drying
  • Humans
  • Male
  • Vaccines, Attenuated / administration & dosage
  • Vaccines, Attenuated / immunology

Substances

  • Chickenpox Vaccine
  • Vaccines, Attenuated