Objective: To analyse and find out the influence of varicella vaccine inoculation to varicella morbidity.
Methods: The case-control study was conducted. During October 1st 2006 to July 31st 2007, 193 varicella cases were identified, and 342 control subjects were matched.
Results: 1. The proportion of nonvaccinated in case group was higher than that of control group (odds ratio 1.49, 95% confidence interval 0.99-2.24, P=0.043). 2. The morbidity to the people who received one dose varicella vaccine was obviously higher than that of people who reiceived more than 2 dose (odds ratio 3.04, 95% confidence interval 1.25-7.72, P=0.007). 3. Significant differences were not observed between the domestic vaccine and the impoted vaccine (odds ratio 1.38, 95% confidence interval 0.53-3.71 P=0.483). 4. Clinical symptom of the vaccine was lighter than that of the unvaccinated, and rash was not typical.
Conclusion: 1. Inoculation varicella vaccine was effective measures to prevent varicella. 2. The risk to get varicella of one-dose vaccinated was higher than that of more than 2-dose vaccinated. 3. The effectiveness of domestic varicella vaccine was as high as impoted vaccine. 4. The clinical symptom of varicella would be alleviated if the person had vaccinated.