Varicella is an acute, highly contagious respiratory and caused by Varicella-zoster virus (VZV). After the primary infection, VZV induce Varicella, then the virus remains dormant in sensory nerve roots in life. Upon the reactivation, shingles can occur. Most of patients can recovery very soon, but kinds of potentially severe complication can induce death. Nowadays the VZV vaccination isn't included in the expanded immunization program in our country. Varicella outbreaks take place at times in the middle of children of our country. The paper offers concise description about pathogen characteristics, diagnosis methods, clinical character, epidemiology knowledge and strategy of prevention.