EEG topography-specific BOLD changes: a continuous EEG-fMRI study in a patient with focal epilepsy

Mirco Cosottini; Ilaria Pesaresi; Patrizia Maritato; Gina Belmonte; Arianna Taddei; Ferdinando Sartucci; Mario Mascalchi; Luigi Murri

doi:10.1016/j.mri.2009.11.011

EEG topography-specific BOLD changes: a continuous EEG-fMRI study in a patient with focal epilepsy

Magn Reson Imaging. 2010 Apr;28(3):388-93. doi: 10.1016/j.mri.2009.11.011. Epub 2010 Jan 13.

Authors

Mirco Cosottini¹, Ilaria Pesaresi, Patrizia Maritato, Gina Belmonte, Arianna Taddei, Ferdinando Sartucci, Mario Mascalchi, Luigi Murri

Affiliation

¹ Department of Neuroscience University of Pisa, 56100 Pisa, Italy. mircocosottini@libero.it

PMID: 20071117
DOI: 10.1016/j.mri.2009.11.011

Abstract

Blood oxygenation level dependent (BOLD) response related to interictal activity was evaluated in a patient with post-traumatic focal epilepsy at repeated continuous electroencephalogram (EEG)-functional magnetic resonance imaging examinations. Lateralized interictal EEG activity induced a main cluster of activation co-localized with the anatomical lesion. Spreading of EEG interictal activity to both frontal lobes evoked bilateral clusters of activation indicating that topography of BOLD response might depend on the spatial distribution of epileptiform activity.

Publication types

Case Reports

MeSH terms

Adult
Brain / physiopathology*
Brain Mapping / methods*
Electroencephalography / methods*
Epilepsies, Partial / diagnosis*
Epilepsies, Partial / physiopathology*
Humans
Magnetic Resonance Imaging / methods*
Male