[Physicochemical aspects of the antiseptic action of nanohydroxyapatite]

Biofizika. 2009 Nov-Dec;54(6):1045-50.
[Article in Russian]

Abstract

The mechanism of interaction of nanocrystals of hydroxyapatite with Staphylococcus aureus bacteria has been investigated. It was shown that the growth of bacteria and their colonies both in the presence and absence of hydroxyapatite nanocrystals can be described using the Fokker-Planck equation. It was found that hydroxyapatite nanocrystals adhere in a particular orientation on the surface of bacteria, decreasing substantially their colony-forming ability.

MeSH terms

  • Anti-Infective Agents, Local / chemistry
  • Anti-Infective Agents, Local / pharmacology*
  • Chemical Phenomena
  • Crystallization
  • Hydroxyapatites / chemistry
  • Hydroxyapatites / pharmacology*
  • Nanostructures
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / growth & development
  • Suspensions

Substances

  • Anti-Infective Agents, Local
  • Hydroxyapatites
  • Suspensions