Severe alcohol hand rub overdose inducing coma, watch after H1N1 pandemic

Neurocrit Care. 2010 Jun;12(3):400-2. doi: 10.1007/s12028-009-9319-4.

Abstract

Background: Alcoholic hand rubs (AHRs) have been proven effective in preventing nosocomial infections, and healthcare authorities include AHRs use among quality-of-care criteria. Since the onset of the influenza A (H1N1) pandemic, AHRs have gained considerable popularity among the general public.

Methods: We report a case of intentional AHRs self-poisoning inducing rapid coma with hyperlactatemia, and a full recovery. The relevant literature was reviewed. To our knowledge, this is the third reported case of intentional AHRs poisoning. 3 patients presented with a picture of acute alcohol intoxication, of variable severity depending on the amount ingested and speed of ingestion.

Results: The blood alcohol level was 414 mg/dl and tests for other drugs were performed 30 min after admission. The blood lactate level increased briefly to 4.8 mmol/l, without renal or hepatic function disturbances. She regained consciousness after 6 h then achieved a full recovery allowing extubation and readmission to the psychiatric ward after 24 h. She reported gulping down the entire contents of the Aniosgel bottle.

Conclusion: Whereas overdrinking in social settings (wine and liquor) leads to a gradual increase in blood alcohol levels, AHRs poisoning is usually characterized by a sudden massive alcohol load. The unusual nature of the alcohol source may lead to diagnostic wanderings. AHRs are currently available in bottles that facilitate the ingestion of large amounts. Unit-dose packaging or dispensing might decrease the risk of AHRs poisoning.

MeSH terms

  • Adult
  • Alcoholic Intoxication / blood
  • Alcoholic Intoxication / etiology*
  • Coma / blood
  • Coma / chemically induced*
  • Cross Infection / prevention & control*
  • Cross Infection / transmission
  • Disease Outbreaks*
  • Disinfectants / poisoning*
  • Drug Overdose / blood
  • Drug Overdose / etiology*
  • Ethanol / blood
  • Ethanol / poisoning*
  • Female
  • Hand Disinfection*
  • Humans
  • Influenza A Virus, H1N1 Subtype*
  • Influenza, Human / prevention & control*
  • Influenza, Human / transmission
  • Lactic Acid / blood
  • Neurologic Examination / drug effects
  • Suicide, Attempted*

Substances

  • Disinfectants
  • Lactic Acid
  • Ethanol