When do psychogenic nonepileptic seizures occur on a video/EEG telemetry unit?

Abstract

To maximize the efficiency of diagnostic video/EEG telemetry, we retrospectively studied the occurrence of clinical events during admission in 254 patients. One hundred fifty-nine patients had psychogenic nonepileptic seizures (PNES) and 95 had epileptic seizures (ES). Twenty-five with PNES and none with ES had an event before or during electrode placement (P<0.0001). In the remaining 229, the initial event occurred within 48 hours of electrode placement in 98.5% patients with PNES and 100.0% of patients with ES. Time to occurrence of initial event did not differ between groups (P=0.69). 17.1% patients with PNES and 51.6% with ES had events between 12 AM and 6 AM (P=0.001). In conclusion, during diagnostic video/EEG telemetry, most patients who experience PNES or ES have diagnostic, typical events within 2 days. Although time to initial event after electrode placement does not differ between diagnoses, events prior to or during placement are most likely PNES and events at night are most likely ES.