Predictors of psychiatric disorders following traumatic brain injury

J Head Trauma Rehabil. 2010 Sep-Oct;25(5):320-9. doi: 10.1097/HTR.0b013e3181c8f8e7.

Abstract

Objective: To investigate predictors of posttraumatic brain injury psychiatric disorders.

Design: Retrospective, cross-sectional design with stratified random sampling of groups of patients on average 1 to 5 years postinjury. DSM-based diagnostic interviews of both traumatic brain injury (TBI) participant and informant.

Participants: One hundred community-based participants, aged 19-74 years, with traumatic brain injury sustained 0.05-5.5 years previously.

Setting: Community-based patients previously treated at a rehabilitation hospital.

Main measure: The Structured Clinical Interview for DSM-IV diagnosis.

Results: A psychiatric history was a high-risk factor for having the same disorder postinjury. However, the majority of cases of depression and anxiety were novel, suggesting that significant factors other than pre-TBI psychiatric status contribute to post-TBI psychiatric outcome. Female gender, lower education, and pain were also associated with postinjury depression and unemployment and older age with anxiety.

Conclusion: Findings suggest that long-term screening and support are important for individuals with TBI, regardless of preinjury psychiatric status.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Anxiety / etiology*
  • Brain Injuries / complications*
  • Brain Injuries / rehabilitation
  • Cross-Sectional Studies
  • Depression / etiology*
  • Educational Status
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mood Disorders / etiology*
  • Multivariate Analysis
  • Odds Ratio
  • Pain
  • Retrospective Studies
  • Sex Factors
  • Substance-Related Disorders / etiology*
  • Unemployment