Results of total hip arthroplasties in the young patient; further evidence for a barrier against articular wear debris by hydroxyapatite coatings

Hip Int. 2009 Oct-Dec;19(4):343-51. doi: 10.1177/112070000901900408.

Abstract

We examined the hypothesis that the circumferential osseous apposition around HA-coated implants forms a protective barrier against articular wear debris. Sixty-five hydroxyapatite-coated total hip arthroplasties in 57 patients (age <50years) with polyethylene-metal articulation were evaluated regarding PE-wear, osteolysis, and clinical outcome at a minimum of 10 years follow-up. There was no correlation between PE-wear and osteolysis of the femoral zones or cup zones I and III. A strong Pearson correlation was found between polyethylene wear and osteolysis around cup zone II, where the cup only consisted of polyethylene (p<0,01). The aseptic failure rate was 1.5% for the femoral component and 4.5% for the cup after 10 years of follow-up. The average Harris Hip Score was 90 and the average Engh score for fixation was 23 after 10 years . Around HA-coated parts of the prosthesis bone formation remained stable, regardless of the degree of polyethylene wear. The average linear polyethylene wear was 0,16 mm/year. The circumferential osseous apposition of the HA-coated implants possibly formed a protective barrier against articular wear debris. The use of cups with a backside gap resulted in PE-wear associated osteolysis in cup zone II and may be considered to be best avoided.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Arthroplasty, Replacement, Hip / instrumentation*
  • Coated Materials, Biocompatible*
  • Equipment Failure Analysis
  • Female
  • Follow-Up Studies
  • Hip / diagnostic imaging
  • Hip Prosthesis* / adverse effects
  • Humans
  • Hydroxyapatites*
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Osteolysis
  • Polyethylene
  • Prospective Studies
  • Prosthesis Design*
  • Radiography
  • Surface Properties
  • Young Adult

Substances

  • Coated Materials, Biocompatible
  • Hydroxyapatites
  • Polyethylene