Sensitive, selective and label-free protein detection using a smart polymeric transducer and aptamer/ligand system

Chem Commun (Camb). 2009 Dec 21:(47):7357-9. doi: 10.1039/b918241a. Epub 2009 Oct 22.

Abstract

We have demonstrated a smart polymeric transducer and aptamer/intercalating dye system that allows the label-free detection of protein with high sensitivity and selectivity.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aptamers, Nucleotide / chemistry*
  • Base Sequence
  • Fluorescence Resonance Energy Transfer / methods*
  • Ligands
  • Polymers / chemistry*
  • Proteins / analysis*
  • Proteins / chemistry

Substances

  • Aptamers, Nucleotide
  • Ligands
  • Polymers
  • Proteins