Ultrasound-assisted dehydrogenation of 5-acetyl-3,4-dihydropyrimidin-2(1H)-ones

Hamid Reza Memarian; Asadollah Farhadi; Hassan Sabzyan

doi:10.1016/j.ultsonch.2009.11.014

Ultrasound-assisted dehydrogenation of 5-acetyl-3,4-dihydropyrimidin-2(1H)-ones

Ultrason Sonochem. 2010 Mar;17(3):579-86. doi: 10.1016/j.ultsonch.2009.11.014. Epub 2009 Nov 26.

Authors

Hamid Reza Memarian¹, Asadollah Farhadi, Hassan Sabzyan

Affiliation

¹ University of Isfahan, Faculty of Science, Department of Chemistry, Isfahan 81746-73441, Islamic Republic of Iran. memarian@sci.ui.ac.ir

PMID: 20022547
DOI: 10.1016/j.ultsonch.2009.11.014

Abstract

In this study, various 5-acetyl-3,4-dihydropyrimidin-2(1H)-ones were synthesized and the dehydrogenation of these compounds by potassium peroxydisulfate in aqueous acetonitrile under thermal and sono-thermal conditions were investigated. Whereas the effect of the nature of 4-substituent influences the rate of reaction, the application of sonic waves decreases drastically the time of thermal reaction.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Hydrogenation
Kinetics
Models, Molecular
Molecular Conformation
Pyrimidines / chemistry*
Pyrimidinones / chemistry
Solvents / chemistry
Sonication
Ultrasonics*

Substances

Pyrimidines
Pyrimidinones
Solvents