Neuronal signaling pathways: genetic insights into the pathophysiology of major mental illness

Neuropsychopharmacology. 2010 Jan;35(1):350-1. doi: 10.1038/npp.2009.137.

Authors

Russell L Margolis¹, Christopher A Ross

Affiliation

¹ Division of Neurobiology, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA. rmargoli@jhmi.edu

No abstract available

MeSH terms

Animals
Glycogen Synthase Kinase 3 / genetics
Glycogen Synthase Kinase 3 / metabolism
Glycogen Synthase Kinase 3 beta
Humans
Mental Disorders / drug therapy
Mental Disorders / genetics*
Mental Disorders / physiopathology*
Nerve Tissue Proteins / genetics
Nerve Tissue Proteins / metabolism
Neuregulin-1 / genetics
Neuregulin-1 / metabolism
Neurons / physiology*
Schizophrenia / drug therapy
Schizophrenia / genetics
Schizophrenia / physiopathology
Signal Transduction / genetics
Wnt Proteins / genetics
Wnt Proteins / metabolism
beta Catenin / genetics
beta Catenin / metabolism

Substances

DISC1 protein, human
Nerve Tissue Proteins
Neuregulin-1
Wnt Proteins
beta Catenin
Glycogen Synthase Kinase 3 beta
Glycogen Synthase Kinase 3