Abstract
We present the crystal structure of the extracytoplasmic domain of the Bacillus subtilis PhoR sensor histidine kinase, part of a two-component system involved in adaptation to low environmental phosphate concentrations. In addition to the PhoR structure, we predict that the majority of the extracytoplasmic domains of B. subtilis sensor kinases will adopt a fold similar to the ubiquitous PAS domain.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amino Acid Sequence
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Bacillus subtilis / chemistry*
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Bacillus subtilis / genetics
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Bacterial Proteins / chemistry*
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Bacterial Proteins / genetics
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Crystallography, X-Ray
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Models, Molecular
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Molecular Sequence Data
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Protein Kinases / chemistry*
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Protein Kinases / genetics
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Protein Structure, Tertiary
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Sequence Alignment
Substances
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Bacterial Proteins
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PhoR protein, Bacteria
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Protein Kinases