Abstract
A new metabolite, 7-hydroxyjanthinone (1), was isolated from the mangrove endophytic fungus Penicillium sp. (SBE-8), together with two known compounds, janthinone (2) and citrinin (3). The structures of these compounds were identified by spectroscopic methods. Compounds 1 and 2 showed no cytotoxicity against KB and KBv cell lines when tested by the MTT method, but compound 3 was weakly active.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibiotics, Antineoplastic / biosynthesis*
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Antibiotics, Antineoplastic / chemistry*
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Coloring Agents
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Fermentation
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Heterocyclic Compounds, 3-Ring / chemistry*
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Heterocyclic Compounds, 3-Ring / metabolism*
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Humans
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KB Cells
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Magnetic Resonance Spectroscopy
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Penicillium / chemistry*
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Penicillium / metabolism*
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Rhizophoraceae / microbiology*
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Spectrometry, Mass, Electrospray Ionization
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
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Tetrazolium Salts
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Thiazoles
Substances
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7-hydroxyjanthinone
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Antibiotics, Antineoplastic
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Coloring Agents
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Heterocyclic Compounds, 3-Ring
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Tetrazolium Salts
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Thiazoles
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thiazolyl blue