Development of a realistic head model for EEG event-detection and source localization in newborn infants

Annu Int Conf IEEE Eng Med Biol Soc. 2009:2009:2296-9. doi: 10.1109/IEMBS.2009.5335052.

Abstract

In this work we present an integrated method for electroencephalography (EEG) source localization in newborn infants, based on a realistic head model. To build a realistic head model we propose an interactive hybrid segmentation method for T1 magnetic resonance images (MRI), consisting of active contours, fuzzy c-means (FCM) clustering and mathematical morphology. Subsequently, we solve the localization problem using a spike train detection algorithm and an algorithm that deals with the forward and inverse problem. The performance of this fused method indicates that our realistic head model is suitable for the accurate localization of the EEG activity. We will present both initial qualitative and quantitative results.

MeSH terms

  • Algorithms
  • Brain / pathology
  • Brain Mapping / methods
  • Cluster Analysis
  • Electroencephalography / instrumentation*
  • Electroencephalography / methods*
  • Fuzzy Logic
  • Head / pathology*
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging / methods*
  • Models, Statistical
  • Models, Theoretical
  • Phantoms, Imaging