Objective: To explore the changes of sera S100B and NO and their significance of patients with brain injury.
Method: We detected sera S100B and NO level of 30 healthy persons and 108 cases with brain injury by ELISA and method.
Results: The sera S100B level of patient group was increased after 12 h brain injury,and sera NO concentrations of serve type were significantly high than control group, P < 0.01. NO concentrations of serve type, middle type and minor type were significantly high than control group, middle type and minor type group. P < 0.05, However, sera NO level of middle type and minor type group of brain injury had no significance than control group, P > 0.05.
Conclusion: Sera S100B examinations can be indices as diagnosis of early brain injury.