Abstract
The 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions (635 kb and 127 kb). The strain is resistant to a wide range of antibiotics, antiseptics, and heavy metals due to resistance genes encoded on mobile genetic elements and also mutations in housekeeping genes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Anti-Infective Agents, Local / pharmacology
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Drug Resistance, Multiple, Bacterial / genetics*
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Genome, Bacterial / genetics*
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Metals, Heavy / toxicity
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Methicillin-Resistant Staphylococcus aureus / drug effects
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Methicillin-Resistant Staphylococcus aureus / genetics*
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Models, Genetic
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Molecular Sequence Data
Substances
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Anti-Bacterial Agents
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Anti-Infective Agents, Local
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Metals, Heavy
Associated data
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GENBANK/FN433596
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GENBANK/FN433597
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GENBANK/FN433598