Barlerisides A and B, new potent superoxide scavenging phenolic glycosides from Barleria acanthoides

J Enzyme Inhib Med Chem. 2009 Dec;24(6):1332-5. doi: 10.3109/14756360902887046.

Abstract

Barlerisides A (1) and B (2), new phenolic glycosides, have been isolated from the n-butanol soluble sub-fraction of Barleria acanthoides along with two known compounds acteoside (3) and p-hydroxycinnamic acid (4). Their structures have been assigned on the basis of spectral studies. Both 1 and 2 showed significant activity in the superoxide scavenging assay while weak inhibitory activity was observed against the enzyme xanthine oxidase.

MeSH terms

  • Acanthaceae / chemistry*
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology
  • Flavones / chemistry
  • Flavones / isolation & purification*
  • Flavones / pharmacology
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radical Scavengers / pharmacology
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Glucosides / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Phenols / chemistry*
  • Phenols / isolation & purification
  • Phenols / pharmacology
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Solvents / chemistry
  • Superoxides / metabolism*
  • Xanthine Oxidase / antagonists & inhibitors
  • Xanthine Oxidase / metabolism

Substances

  • Anti-Inflammatory Agents
  • Flavones
  • Free Radical Scavengers
  • Glucosides
  • Glycosides
  • Phenols
  • Plant Extracts
  • Solvents
  • barleriside A
  • barleriside B
  • Superoxides
  • Xanthine Oxidase