Long-term follow up of abdominal rectosigmoidectomy with posterior end-to-side stapled anastomosis for Chagas megacolon

Colorectal Dis. 2011 Mar;13(3):317-22. doi: 10.1111/j.1463-1318.2009.02128.x.

Abstract

Aim: Chagas' disease is an endemic parasitosis found in Latin America. The disease affects different organs, such as heart, oesophagus, colon and rectum. Megacolon is the most frequent long-term complication, caused by damage to the myoenteric and submucous plexus, ultimately leading to a functional barrier to the faeces. Patients with severe constipation are managed surgically. The study aimed to analyse the 10-year minimum functional outcome after rectosigmoidectomy with posterior end-to-side anastomosis (RPESA).

Method: A total of 21 of 46 patients were available for follow up. Patients underwent clinical, radiological and manometric evaluation, and the results were compared with preoperative parameters.

Results: Of the 21 patients evaluated, 81% (17) were female, with a mean age of 60.6 years. Good function was achieved in all patients, with significant improvement in defaecatory frequency (P < 0.0001), usage of enemas (P < 0.0001) and patient satisfaction. Barium enema also showed resolution of the colonic and rectal dilatation in 19 cases evaluated postoperatively.

Conclusion: Minimal 10-year follow up of RPESA showed excellent functional results, with no recurrence of constipation.

MeSH terms

  • Adult
  • Aged
  • Anal Canal / physiology
  • Anastomosis, Surgical / adverse effects
  • Anastomosis, Surgical / methods
  • Chagas Disease / complications*
  • Colon / anatomy & histology
  • Colon / diagnostic imaging
  • Colon, Sigmoid / surgery*
  • Constipation / surgery
  • Defecation
  • Digestive System Surgical Procedures / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Laxatives / therapeutic use
  • Male
  • Manometry
  • Megacolon / etiology
  • Megacolon / parasitology
  • Megacolon / surgery*
  • Middle Aged
  • Radiography
  • Rectum / surgery*
  • Time Factors
  • Treatment Outcome
  • Young Adult

Substances

  • Laxatives