Unusual variants of malignant melanoma

Clin Dermatol. 2009 Nov-Dec;27(6):564-87. doi: 10.1016/j.clindermatol.2008.09.015.

Abstract

Melanoma is as diverse in its presentation as it can be in its behavior. This contribution will review the clinical and histologic features of some of the more unusual variants of malignant melanoma that clinicians and pathologists are likely to encounter. There will be a disproportionate focus on the histopathology and prognosis because the clinical presentation of these lesions is in most cases, elusive, and in some cases, frankly deceptive. The discussion will include desmoplastic melanoma, nevoid melanoma, spitzoid melanoma, angiotropic melanoma, and malignant blue nevus.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Needle
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Male
  • Melanoma / diagnosis
  • Melanoma / mortality
  • Melanoma / pathology*
  • Melanoma / therapy
  • Melanoma, Amelanotic / diagnosis
  • Melanoma, Amelanotic / pathology
  • Middle Aged
  • Neoplasm Invasiveness / pathology
  • Neoplasm Staging
  • Nevus, Blue / diagnosis
  • Nevus, Blue / pathology*
  • Nevus, Epithelioid and Spindle Cell / diagnosis
  • Nevus, Epithelioid and Spindle Cell / pathology*
  • Nevus, Pigmented / diagnosis
  • Nevus, Pigmented / pathology*
  • Prognosis
  • Sentinel Lymph Node Biopsy
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / mortality
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / therapy
  • Survival Analysis
  • Young Adult