DNA templated nucleophilic aromatic substitution reactions for fluorogenic sensing of oligonucleotides

Chem Commun (Camb). 2009 Nov 21:(43):6586-8. doi: 10.1039/b912896d. Epub 2009 Oct 5.

Abstract

We have developed an S(N)Ar reaction-triggered fluorescence probe using a new fluorogenic compound derivatized from 7-aminocoumarin for oligonucleotides detection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry*
  • Fluorescent Dyes / chemistry*
  • Oligonucleotides / chemistry*

Substances

  • Fluorescent Dyes
  • Oligonucleotides
  • DNA