Objective: To observe the hair development after subcutaneous implantation of embryonic skin cells in nude mice, and construct a model of hair development.
Methods: Dermal and epidermal cells isolated from embryonic mouse skin were mixed at a given ratio and injected subcutaneously in nude mice, and hair formation after the implantation was observed under a microscope.
Results: Formation of the hair follicles and fibers under the skin of the recipient nude mice and emergence of the hair shaft were observed microscopically.
Conclusion: Embryonic skin cells be used to construct a complete model of hair development after implantation in vivo.