Immunologic response of unvaccinated workers exposed to anthrax, Belgium

Emerg Infect Dis. 2009 Oct;15(10):1637-40. doi: 10.3201/eid1510.081717.

Abstract

To determine immunologic reactivity to Bacillus anthrax antigens, we conducted serologic testing of workers in a factory that performed scouring of wool and goat hair. Of 66 workers, approximately 10% had circulating antibodies or T lymphocytes that reacted with anthrax protective antigen. Individual immunity varied from undetectable to high.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthrax / immunology*
  • Anthrax Vaccines / administration & dosage*
  • Antibodies, Bacterial / blood
  • Bacillus anthracis / immunology
  • Belgium
  • Blotting, Western
  • Cell Proliferation
  • Enzyme-Linked Immunosorbent Assay
  • Humans
  • Inhalation Exposure
  • Occupational Exposure*
  • T-Lymphocytes / cytology
  • T-Lymphocytes / physiology

Substances

  • Anthrax Vaccines
  • Antibodies, Bacterial