[Portal vein thrombosis after splenectomy in childhood: report of 4 cases]

Arch Pediatr. 2009 Nov;16(11):1477-80. doi: 10.1016/j.arcped.2009.08.005. Epub 2009 Oct 7.
[Article in French]

Abstract

Portal vein thrombosis is a major complication of splenectomy. Its frequency is underestimated because of asymptomatic cases. Mesenteric occlusion with intestinal infarcts is the first cause of mortality. Secondarily, in the absence of repermeabilisation, a portal hypertension can occur. We present in this study 4 cases of portal vein thrombosis in childhood. Portal vein thrombosis is frequent (8% of splenectomies) and may be asymptomatic. Doppler postoperative surveillance is justified. Thrombocytosis seems to be a determinant factor. Early diagnosis and treatment may reduce lethal outcome.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Child
  • Female
  • Fibrinolytic Agents / therapeutic use
  • Hemangioma, Cavernous / blood
  • Hemangioma, Cavernous / complications
  • Hemangioma, Cavernous / diagnosis
  • Heparin / therapeutic use
  • Humans
  • Male
  • Mesenteric Artery, Superior
  • Mesenteric Vascular Occlusion / blood
  • Mesenteric Vascular Occlusion / diagnosis
  • Mesenteric Vascular Occlusion / drug therapy
  • Platelet Count
  • Portal Vein*
  • Postoperative Complications / blood
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / drug therapy
  • Recurrence
  • Risk Factors
  • Splenectomy*
  • Splenic Vein
  • Thrombocytosis / blood
  • Thrombocytosis / complications
  • Thrombosis / blood
  • Thrombosis / diagnosis*
  • Thrombosis / drug therapy
  • Ultrasonography, Doppler
  • Vascular Neoplasms / blood
  • Vascular Neoplasms / complications
  • Vascular Neoplasms / diagnosis

Substances

  • Fibrinolytic Agents
  • Heparin