P450 enzymes: their structure, reactivity, and selectivity-modeled by QM/MM calculations

Chem Rev. 2010 Feb 10;110(2):949-1017. doi: 10.1021/cr900121s.

Authors

Sason Shaik¹, Shimrit Cohen, Yong Wang, Hui Chen, Devesh Kumar, Walter Thiel

Affiliation

¹ Institute of Chemistry and the Lise-Meitner-Minerva Center for Computational Quantum Chemistry, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel. sason@yfaat.ch.huji.ac.il

PMID: 19813749
DOI: 10.1021/cr900121s

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biocatalysis
Cytochrome P-450 Enzyme System / chemistry*
Cytochrome P-450 Enzyme System / metabolism
Models, Molecular
Oxidation-Reduction
Protein Isoforms / chemistry
Protein Isoforms / metabolism
Protons
Quantum Theory
Static Electricity

Substances

Protein Isoforms
Protons
Cytochrome P-450 Enzyme System