Synchronous renal cell carcinoma and multiple myeloma: report of two cases and review of the literature

M A Ozturk; F Dane; I Kaygusuz; O Asmaz; A Uzay; M Bayik; N S Turhal

Synchronous renal cell carcinoma and multiple myeloma: report of two cases and review of the literature

J BUON. 2009 Jul-Sep;14(3):511-4.

Authors

M A Ozturk¹, F Dane, I Kaygusuz, O Asmaz, A Uzay, M Bayik, N S Turhal

Affiliation

¹ Department of Internal Medicine, Marmara University School of Medicine, Istanbul, Turkey. ozturkakif@yahoo.com

PMID: 19810147

Abstract

Coexistence of renal cell carcinoma (RCC) and multiple myeloma (MM) is an extremely rare condition. Appearance of synchronous RCC and MM was not reported independently so far. In this brief communication, we report 2 cases of synchronous RCC and MM, discuss common risk factors or pathogenetic mechanisms seen in either RCC or MM, point out the importance of IL-6 in this coexistence and provide some descriptive properties of all reported synchronous RCC and MM cases.

Publication types

Case Reports
Review

MeSH terms

Carcinoma, Renal Cell / diagnosis*
Carcinoma, Renal Cell / epidemiology
Carcinoma, Renal Cell / therapy
Humans
Interleukin-6 / blood
Interleukin-6 / metabolism*
Kidney Neoplasms / diagnosis*
Kidney Neoplasms / epidemiology
Kidney Neoplasms / therapy
Male
Middle Aged
Multiple Myeloma / diagnosis*
Multiple Myeloma / epidemiology
Multiple Myeloma / therapy
Neoplasms, Multiple Primary / diagnosis*
Neoplasms, Multiple Primary / epidemiology
Neoplasms, Multiple Primary / therapy
Risk Factors

Substances

IL6 protein, human
Interleukin-6