Abstract
A variety of sulfonic acids have been trifluoromethylated using 1-trifluoromethyl-1,2-benziodoxol-3(1H)-one under mild conditions in good to excellent yields. Initial mechanistic investigations of this reaction show a clean second-order kinetics and only very weak substrate electronic effects.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkanesulfonates / chemistry*
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Allyl Compounds
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Hydrocarbons, Halogenated / chemistry*
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Iodine
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Methylation
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Molecular Structure
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Sulfonic Acids / chemistry*
Substances
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1-trifluoromethyl-1,2-benziodoxol-3(1H)-one
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Alkanesulfonates
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Allyl Compounds
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Hydrocarbons, Halogenated
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Sulfonic Acids
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Iodine