Nursing some sense out of Myc

J Biol. 2009 Sep 28;8(8):77. doi: 10.1186/jbiol181.

Abstract

Data recently published in BMC Biology provide insights into the normal physiological function of c-myc in the development and regeneration of the mammary gland and indicate a key role in epithelial cell proliferation, elaboration of ductal alveoli, and the biosynthetic capacity and milk production of the mature organ.

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Cell Proliferation
  • Epithelial Cells / cytology
  • Female
  • Humans
  • Lactation
  • Mammary Glands, Human / embryology
  • Mammary Glands, Human / physiology*
  • Neoplasms / drug therapy
  • Neoplasms / genetics
  • Proto-Oncogene Proteins c-myc / antagonists & inhibitors
  • Proto-Oncogene Proteins c-myc / physiology*
  • Regeneration

Substances

  • Antineoplastic Agents
  • Proto-Oncogene Proteins c-myc