Staphylococcus aureus host cell invasion and post-invasion events

Int J Med Microbiol. 2010 Feb;300(2-3):170-5. doi: 10.1016/j.ijmm.2009.08.019. Epub 2009 Sep 24.

Abstract

Staphylococcus aureus is now recognized as a facultative intracellular pathogen. The aim of this review is to discuss novel data regarding the invasion mechanism and post-invasion events with a focus on the fate of the infected phagosome in non-professional phagocytes and the role of S. aureus alpha-toxin.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacterial Toxins / metabolism
  • Cell Death
  • Host-Pathogen Interactions
  • Humans
  • Phagocytes / immunology
  • Phagocytes / metabolism
  • Phagocytes / microbiology*
  • Phagosomes / immunology
  • Phagosomes / metabolism
  • Phagosomes / microbiology
  • Staphylococcal Infections / immunology
  • Staphylococcal Infections / metabolism
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / pathogenicity
  • Staphylococcus aureus / physiology*
  • Virulence

Substances

  • Bacterial Toxins