Background: Limited information is available on target lesion revascularization (TLR) after percutaneous coronary intervention (PCI) in unselected patients at the beginning of the drug eluting stent (DES) era.
Methods and results: From January 2000 to September 2004 data from all PCI procedures in Western Denmark were recorded in the Western Danish Heart Registry. A total of 24,701 lesions were treated in 15,542 patients. Lesion length, stent length, frequency of complex lesions and age increased from 2000 to 2004. The use of DES increased from 0% in 2000, 2001, 2002 to 34% in 2003 and 54.0% in 2004 of all stents used. The clinical driven TLR declined from 9.4% in 2000 to 5.4% in 2004. The use of DES (OR 0.60; 95% CI 0.39-0.92, p=0.018) and procedure year (OR 0.89; 95% CI 0.83-0.97, p=0.008) and restenotic lesion (OR 1.51; 95% CI 1.18-1.93, p=0.001) were independent predictors of a TLR. Similar TLR rates were observed in diabetics (7.7%) and non-diabetic (7.0), p=NS.
Conclusion: In unselected PCI patients the TLR rate declined from 2000 to 2004. The use of DES was an independent predictor of TLR.