Abstract
A study on the genetic diversity of HIV-1 subtypes present along the coastal strip of Kenya, i.e., Kilifi, Mombasa, Msambweni, and Malindi districts, was carried out. DNA sequences for regions encoding a portion of the env-gp41 region of the virus were generated by PCR and sequenced directly. Eighty six samples that were successfully sequenced were analyzed. From the analysis, 86% (74) were subtype A1, 5% (4) were subtype C, 8% (7) were subtype D, and 1% (1) was subtype G. This study shows that HIV-1 subtype A1 is the most dominant subtype in circulation in this region.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cluster Analysis
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Genetic Variation*
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Genotype
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HIV Envelope Protein gp41 / genetics
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HIV Infections / virology*
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HIV-1 / classification*
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HIV-1 / genetics*
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HIV-1 / isolation & purification
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Humans
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Kenya
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Molecular Sequence Data
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Polymerase Chain Reaction
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Sequence Analysis, DNA
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Sequence Homology
Substances
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HIV Envelope Protein gp41
Associated data
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GENBANK/FJ610669
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GENBANK/FJ610670
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GENBANK/FJ610671
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GENBANK/FJ610672
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GENBANK/FJ610673
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GENBANK/FJ610674
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GENBANK/FJ610675
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GENBANK/FJ610676
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GENBANK/FJ610677
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GENBANK/FJ610678
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GENBANK/FJ610679
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GENBANK/FJ610680
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GENBANK/FJ610686
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GENBANK/FJ610687
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GENBANK/FJ610688
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GENBANK/FJ610689
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GENBANK/FJ610690
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GENBANK/FJ610691
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GENBANK/FJ610692
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GENBANK/FJ610693
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GENBANK/FJ610695
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GENBANK/FJ610697
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GENBANK/FJ610698
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GENBANK/FJ610699
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