The Brugada syndrome is an inherited channelopathy associated with a high propensity of ventricular tachyarrhythmias and sudden cardiac death in individuals with structurally normal hearts. Recent data are indicative of mild structural changes, mainly involving the right ventricle, in patients with Brugada syndrome. We present the case of a patient with cardiac amyloidosis due to multiple myeloma who presented with pre-syncopal episodes and intermittent Brugada-like ECG pattern.
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