Sequence divergency of the cytadhesin gene of Mycoplasma pneumoniae

Infect Immun. 1990 Aug;58(8):2669-74. doi: 10.1128/iai.58.8.2669-2674.1990.

Abstract

The Mycoplasma pneumoniae cytadhesin P1 genes from two groups of clinical isolates that display restriction fragment length polymorphisms were cloned and sequenced. Within each group the nucleotide sequences were identical, but two major differences were detected between the groups. These two stretches of sequence divergence were located in multiple-copy regions of the P1 gene and resulted in considerable amino acid changes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adhesins, Bacterial*
  • Amino Acid Sequence
  • Amino Acids / analysis
  • Bacterial Proteins / genetics*
  • Base Sequence
  • Cloning, Molecular
  • DNA, Bacterial
  • Genes, Bacterial*
  • Molecular Sequence Data
  • Pneumonia, Mycoplasma / genetics*
  • Polymorphism, Restriction Fragment Length
  • Sequence Homology, Nucleic Acid

Substances

  • Adhesins, Bacterial
  • Amino Acids
  • Bacterial Proteins
  • DNA, Bacterial
  • adhesin, Mycoplasma pneumoniae