A formal synthesis of swainsonine by gold-catalyzed allene cyclization

Org Lett. 2009 Aug 20;11(16):3706-8. doi: 10.1021/ol901094h.

Abstract

A formal synthesis of swainsonine has been achieved using a highly efficient and diastereoselective gold(III)-catalyzed allene cyclization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Cyclization
  • Gold Compounds / chemistry*
  • Molecular Structure
  • Swainsonine / chemical synthesis*
  • Swainsonine / chemistry

Substances

  • Gold Compounds
  • gold chloride
  • Swainsonine