Abstract
Paget's disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain. Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this disorder.
MeSH terms
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Animals
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Bone Density Conservation Agents / administration & dosage*
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Bone Density Conservation Agents / chemistry
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Bone Density Conservation Agents / therapeutic use*
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Diphosphonates / administration & dosage*
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Diphosphonates / chemistry
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Diphosphonates / therapeutic use*
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Humans
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Imidazoles / administration & dosage
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Imidazoles / chemistry
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Imidazoles / therapeutic use
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Injections, Intravenous
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Osteitis Deformans / drug therapy*
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Pamidronate
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Zoledronic Acid
Substances
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Bone Density Conservation Agents
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Diphosphonates
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Imidazoles
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Zoledronic Acid
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6-amino-1-hydroxyhexane-1,1-diphosphonate
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Pamidronate