Abstract
With the catalysis of CuI/trans-N,N'-dimethylcyclohexane-1,2-diamine, a number of carboxylic acids underwent efficient intramolecular O-vinylation with vinyl bromides leading to the synthesis of the corresponding five- and six-membered enol lactones. The same catalytic system also led to the efficient cycloisomerization of alkynoic acids.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Carboxylic Acids / chemistry*
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Catalysis
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Cyclization
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Diamines / chemistry*
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Lactones / chemical synthesis*
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Stereoisomerism*
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Sulfhydryl Compounds / chemistry
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Vinyl Compounds / chemistry*
Substances
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Carboxylic Acids
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Diamines
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Lactones
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Sulfhydryl Compounds
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Vinyl Compounds
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vinyl bromide