Activity of telomerase in ovarian cancer cells. Clinical implications

J Lubin; J Markowska; A Markowska; J Stanisławiak; T Lukaszewski

Activity of telomerase in ovarian cancer cells. Clinical implications

Clin Exp Obstet Gynecol. 2009;36(2):91-6.

Authors

J Lubin¹, J Markowska, A Markowska, J Stanisławiak, T Lukaszewski

Affiliation

¹ Department of Gynaecological Oncology, Poznan University of Medical Sciences, Poznan, Poland. jolaostap@wp.pl

PMID: 19688950

Abstract

Estimation of telomerase activity in cell nuclei of ovarian malignant tumours may provide an independent prognostic index. The test for telomerase activity in tumour cell nuclei may be accepted as a useful diagnostic test with application for differential diagnoses of benign ovarian tumours vs tumours of a borderline or malignant character.

MeSH terms

Adenocarcinoma / enzymology*
Adult
Aged
CA-125 Antigen / analysis
Case-Control Studies
Cell Nucleus / enzymology*
Female
Humans
In Situ Hybridization, Fluorescence
Middle Aged
Neoplasm Staging
Ovarian Cysts / enzymology
Ovarian Neoplasms / enzymology*
Predictive Value of Tests
Survival Analysis
Telomerase / metabolism*
Ubiquitin-Protein Ligases / analysis

Substances

CA-125 Antigen
BRAP protein, human
Ubiquitin-Protein Ligases
Telomerase