Constituents from fruits of Cupressus sempervirens

Fitoterapia. 2010 Apr;81(3):162-6. doi: 10.1016/j.fitote.2009.08.014. Epub 2009 Aug 15.

Abstract

Two new phenolic glycosides (1, 2), along with fourteen known compounds (3-16) have been isolated from the fruit of Cupressus sempervirens. The structures of these compounds were determined by spectroscopic analysis and were evaluated for their inhibitory activity against glycogen phosphorylase and glucose-6-phosphatase enzymes. Compounds 14 showed a moderate inhibition against glucose-6-phosphatase and 15 against glycogen phosphorylase enzymes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abietanes / chemistry
  • Abietanes / isolation & purification*
  • Abietanes / pharmacology
  • Cupressus / chemistry*
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Diterpenes / pharmacology
  • Enzyme Inhibitors / isolation & purification*
  • Enzyme Inhibitors / pharmacology
  • Fruit
  • Glucose-6-Phosphatase / antagonists & inhibitors*
  • Glycogen Phosphorylase / antagonists & inhibitors*
  • Glycosides / isolation & purification
  • Glycosides / pharmacology
  • Molecular Structure
  • Phenols / isolation & purification
  • Phenols / pharmacology
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology
  • Plant Leaves

Substances

  • 15-acetoxyimbricatolic acid
  • Abietanes
  • Diterpenes
  • Enzyme Inhibitors
  • Glycosides
  • Phenols
  • Plant Extracts
  • ferruginol
  • Glycogen Phosphorylase
  • Glucose-6-Phosphatase