Effects of coronary risk reduction on the pattern of mortality

Lancet. 1990 Feb 3;335(8684):275-7. doi: 10.1016/0140-6736(90)90082-g.

Abstract

Control of coronary risk factors is associated with lower age-specific risks, but people will then live longer, with increased exposure to the higher mortality rates of the elderly. Expected changes in pattern of mortality, based on the 15-year follow-up of men in the Whitehall study, have been calculated. Non-smokers live longer than smokers, but death (when it comes) is more likely to be due to heart attack and less likely to be due to cancer. By contrast a lower level of plasma cholesterol, which is also associated with longer life, is expected to reduce the lifetime risk of fatal heart attack, its place then being taken by a typical mixture of other causes of death.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Age Factors
  • Aged
  • Blood Pressure
  • Cause of Death
  • Cholesterol / blood*
  • Cohort Studies
  • Coronary Disease / blood
  • Coronary Disease / etiology
  • Coronary Disease / prevention & control*
  • Evaluation Studies as Topic
  • Humans
  • Life Expectancy / trends
  • Male
  • Middle Aged
  • Mortality / trends*
  • Quality of Life
  • Risk Factors
  • Smoking / adverse effects*

Substances

  • Cholesterol