Morphology and phase behavior of two-component lipid membranes

J Biol Phys. 2006 Nov;32(5):369-81. doi: 10.1007/s10867-006-9021-0. Epub 2006 Dec 15.

Abstract

The stability and shapes of domains with different bending rigidities in lipid membranes are investigated. These domains can be formed from the inclusion of an impurity in a lipid membrane or from the phase separation within the membrane. We show that, for weak line tensions, surface tensions and finite spontaneous curvatures, an equilibrium phase of protruding circular domains or striped domains may be obtained. We also predict a possible phase transition between the investigated morphologies.